Double Marker Test in Chandigarh
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Double Marker Test
The double marker test or dual marker blood test is normally performed between the 11th and 14th week of the first trimester. It screens for chromosomal abnormalities in the growing fetus. The double marker test proves to be one of the most important tests during pregnancy. At Garbh, we provide expert services for double marker test in Chandigarh. We will help you understand the importance of this test and tell you how it supports the health of both the mother and the baby. This test is one of the best advanced prenatal screenings. Our aim is to help you navigate through one of the key tests during pregnancy. And to ease your mind and empower you with knowledge.
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How Does the Double Marker Test in Pregnancy Work?
This test screens for chromosomal abnormalities in the growing fetus. It is referred to as the dual marker test in pregnancy because it focuses on two specific markers in the mother’s blood:
- Free Beta hCG (Human Chorionic Gonadotropin): It’s a hormone that is produced during pregnancy. Abnormal levels of this hormone can indicate potential chromosomal issues.
- PAPP-A (Pregnancy-Associated Plasma Protein-A): It’s a protein that is produced by the placenta. Low levels of PAPP-A can be related to chromosomal abnormalities such as Down syndrome.
Blood levels of these markers are interpreted in conjugation with NT NB scan and maternal age and results are given as risk ratio. A lower risk suggests a lower chance of chromosomal abnormalities and higher risk suggests higher chance of chromosomal abnormalities like
- Down Syndrome (Trisomy 21): It’s a Chromosomal disorder that causes intellectual disabilities and distinct physical features. The disease is not lethal. Children with Down syndrome can lead fulfilling lives if given proper care and support.
- Edwards Syndrome (Trisomy 18): In this condition, developmental delays and abnormalities happen in the baby. This can result in a shorter life span, in some cases. Babies with this condition need specialized medical attention.
- Patau Syndrome (Trisomy 13): It’s a rare disorder that causes severe intellectual and physical impairments. Sometimes, it is associated with life-threatening complications. The condition can be challenging, but early diagnosis can help in managing the baby’s health
If a high risk of chromosomal abnormalities is observed in a Double marker test, your doctor can advise you on further tests such as NIPT or invasive testing like Chorionic villus sampling or Amniocentesis for definitive diagnosis.
Why Do These Markers Fluctuate?
The levels of Free Beta hCG and PAPP-A can fluctuate for many reasons. These fluctuations reflect the health and development of the foetus and placenta.
Free Beta HCG:
- It is secreted by the cells of the placenta. Its primary role is to support the corpus luteum (a temporary structure in the ovary) in producing progesterone. Progesterone maintains the uterine lining during early pregnancy.
- High levels of free beta hCG may point towards chromosomal abnormalities like Down syndrome. However high levels can also result from multiple pregnancies (e.g. twins) or a molar pregnancy.
- Low levels can suggest a higher risk of miscarriage due to a poorly functioning placenta. It can also be related to conditions like Edwards syndrome.
PAPP-A:
- This protein plays an important role in regulation of the growth and development of the foetus.
- Low levels are generally related to chromosomal abnormalities such as Down syndrome. They may also show complications like restricted fetal growth or pre-eclampsia.
High levels of PAPP-A may sometimes indicate rapid placental growth, which can also be monitored closely.
Why is the Double Marker Test Important?
The double marker test in pregnancy is necessary for early identification of chromosomal abnormalities. Counsellor also generally explain the double marker test price during the initial consultation.
Here’s why it matters:
Early Detection of Risks
The test helps in the detection of risks related to chromosomal abnormalities in the fetus. Parents can make informed decisions about further testing or preparations.Non-Invasive and Safe
This test is not like other diagnostic tests such as amniocentesis. The dual marker blood test is non-invasive. This poses no risk to the mother or baby.Guidance for Further Testing
If the results show a higher risk, the doctor may recommend additional tests like chorionic villus sampling (CVS) or amniocentesis for a definitive diagnosis.
Peace of Mind for Parents
For parents having a family history, a low-risk result can offer inner peace. This helps them enjoy their pregnancy with less anxiety.
Who Should Get the Double Marker Test in Chandigarh?
- Women above the age of 35
- Those with a family history of chromosomal / genetic disorders
- Mothers with a past of pregnancies showing chromosomal abnormalities
- Women with abnormal ultrasound results or other risk factors
Consulting your doctor about the double marker test in Chandigarh is an important step in making sure of a healthy pregnancy.
When is the Double Marker Test Performed?
The double marker test in pregnancy is performed between the 11th and 14th weeks of pregnancy. This particular window is chosen because the said markers can be accurately measured during this period. Your doctor will also advise a NT scan along with a double marker test to give you an overall risk assessment.
How is the Dual Marker Test in Pregnancy Performed?
- A blood sample is taken from the mother.
- The sample is processed in the laboratory for markers.
- The results is combined with other factors, such as maternal age and NT scan measurements to calculate the risk of chromosomal abnormalities.
Scientific Studies Supporting the Test
- Efficacy in Detecting Down Syndrome: A study published in Wiley’s Obstetrics and Gynaecology hub says that combining Free Beta hCG, PAPP-A, and NT scan results achieved a high detection rate for Down syndrome, which in turn reduces the need for invasive procedures.
- Improved Pregnancy Outcomes: Research has shown that identifying low levels of PAPP-A can help doctors monitor the pregnancy closely. This allows them to intervene early and address complications like pre-eclampsia or fetal growth restriction.
Making the Process Less Intimidating
The double marker test in pregnancy is a non-invasive procedure. At Garbh, we know that all this medical information might feel overwhelming, but the test itself is very simple. Many mothers describe it as just another routine part of their prenatal care. You can focus on how this step is helping make sure of your baby’s health. Remember that Our Fetal Medicine consultant is there to guide you through every result and recommendation.
A Step Towards a Healthy Pregnancy
Advanced prenatal screenings like the double marker test are becoming more accessible across India, making sure better care for expecting parents. By taking these simple yet necessary steps, you can feel more confident about your baby’s health and your journey into parenthood. The double marker test in pregnancy is an important step for managing the health and well-being of your baby. It can provide critical insights into early pregnancy, which helps parents and doctors take proactive steps. You can consult Our Fetal Medicine specialist today to learn more about the double marker test and its importance.
Frequently asked questions
The double marker test focuses on two specific markers in the mother’s blood, whereas other screenings, like the triple or quad marker tests, assess additional markers. The double marker test is conducted earlier in pregnancy.
No, the test is not mandatory but is highly recommended for pregnant women.
The test is a simple procedure and requires a blood sample to be taken from the mother and poses no risk to the mother or baby.
No, the test primarily screens for chromosomal abnormalities like Down syndrome. Other genetic conditions may require separate tests.
Speak with your doctor immediately. They may suggest additional diagnostic tests like amniocentesis or CVS for confirmation.
No, fasting is not required for the dual marker blood test.
Results are typically available within a few days.
The test does not predict birth defects but assesses the risk of chromosomal abnormalities.
Coverage varies depending on your insurance provider. It’s best to check with them directly, on priority.
Discussing the double marker test cost with your healthcare provider will help you in better planning. The dual marker test price typically ranges from INR 1500 to INR 2000.
Meet our specialist
At Garbh, our team of highly qualified specialists is dedicated to providing expert care in fetal medicine and genetic counseling. With extensive experience and a compassionate approach, they ensure the best possible care for both mother and baby. Meet our specialists to guide you through every step of your journey with personalized and professional support.
Dr. Trishdeep Singh Grewal
Director, Consultant Radiologist and Fetal Medicine specialist
Dr. Trishdeep, our Director and fetal medicine Specialist, brings nearly five years of dedicated experience to our team. After completing a two-year fellowship in fetal medicine at the prestigious Bangalore Fetal Medicine Centre, he has...
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Excellent facilities
“The care I received at Garbh was exceptional. The team made me feel comfortable and supported throughout my pregnancy.”
Manisha Goyal
Chandigarh
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“Thanks to the expertise at Garbh, my twin pregnancy was managed smoothly, and both my babies are healthy.”
Gurpreet Bajwa
Chandigarh
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Mansi Sehgal
Chandigarh
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